Fig. 1
From: Hierarchical structural component model for pathway analysis of common variants
A schematic diagram of HisCoM-PCA y is the phenotype of subject; pathwayk means kth pathway; Genekt − PCi denotes ith PC of the tth gene in kth pathway; SNPktr is rth SNP of the tth gene in kth pathway; lktr denotes a loading value of SNPktr from PCA; wkti denotes the weight assigned to Genekt − PCi; βk denote the coefficient connecting the kth pathway to the phenotype