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Table 1 Splicing events and DNA methylation altered in the same direction in at least three cancer types

From: Genome-wide analysis reveals the association between alternative splicing and DNA methylation across human solid tumors

Gene nameTumor types altered significantlyCpG siteExonType of ASThe direction of the correlation
ZNF577HNSC,KIRC,KIRP,LUSC,PRADcg11269599, cg10635122, cg035624141.2:1.3RI+
 KIRC,KIRP,PRADcg10783469, cg24794228, cg23010048, cg167312401.2:1.3RI+
  1. Abbreviations: BRAC Breast invasive carcinoma, HNSC Head, and neck squamous cell carcinoma, KIRC Kidney renal clear cell carcinoma, KIRP Kidney renal papillary carcinoma, LUAD Lung adenocarcinoma, LUSC Lung squamous cell carcinoma, PRAD Prostate adenocarcinoma, THCA Thyroid carcinoma, AS Alternative splicing, AP Alternate promoter, RI Retained intron, AT Alternate terminator
  2. “+” represents the positive correlation between PSI values and DNA methylation in the tumor tissues. “-” represents the inverse correlation between PSI values and DNA methylation in the tumor tissues