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Table 2 Simulated mutated genomes used for accurateness testing. The simulated data sets gw1 and gw2 were used to compare the prediction results for a genome-wide prediction. The simulated data sets lcd was used to compare the prediction results for genes for which a prediction of all tested callers was available

From: MetaCNV - a consensus approach to infer accurate copy numbers from low coverage data

Simulation

Depth of coverage

# of amplified genes

# of deleted genes

Total # of genes

Ratio amplified/ deleted genes

sim 1x gw1

1.1x

283

559

13,906

0.51

sim 1x gw2

1.1x

236

573

13,920

0.41

sim 1x lcd

1.5x

25

30

330

0.83

sim 2x gw1

2.2x

247

560

13,937

0.44

sim 2x gw2

2.2x

254

588

13,922

0.43

sim 2x lcd

2.9x

42

44

16

0.95

sim 5x gw1

5.7x

230

580

13,987

0.40

sim 5x gw2

5.7x

251

593

13,949

0.42

sim 5x lcd

7.3x

62

48

14

1.29

sim 10x gw1

11.3x

263

560

13,882

0.47

sim 10x gw2

11.3x

240

551

13,865

0.44

sim 10x lcd

14.9x

54

49

7

1.10