Fig. 4

Correlation between corresponding LBC and FFPE specimens in VAF, Mutation counts, TMB, and MSI. a The VAF of mutated genes obtained from 7 endometrial LBC and that of the same gene mutations from corresponding FFPE were plotted, showing a good correlation between the selected LBC and FFPE specimens. The data consisted of VAF of 42 genes detected by NGS analysis in 7 cases with paired LBC and biopsy specimens. b Concordance of mutation counts, TMB, and MSI scores in paired LBC and FFPE (biopsy and resection) specimens from the 7 cases. Bx, biopsy; SR, surgical resection; L, LBC; MMR-D, mismatch repair protein deficiency