Haplotyping by linked-read sequencing (HLRS) of the genetic disease carriers for preimplantation genetic testing without a proband or relatives

Table 1 10× Genomics sequencing summary

Sample	G2018004A_LYL	G2018004B_LGB	G2018001A_LSL
Input DNA Molecular Length	21,858 bp	24,088 bp	22,631 bp
Number of Reads	1091.38 M	937.20 M	776.89 M
Mapped Reads	95.9%	94.9%	95.6%
Median Insert Size	365 bp	360 bp	363 bp
Mean Depth	47.4×	40.0×	33.5×
SNPs Phased	99.2%	98.4%	98.9%
Longest Phase Block	5,080,496 bp	5,421,595 bp	3,620,840 bp
N50 Phase Block	775,060 bp	840,402 bp	684,981 bp

ISSN: 1755-8794