Fig. 2

The consensus matrix for DNA methylation classification with the corresponding heat map. a The colour-coded heatmap corresponding to the consensus matrix for k = 7 obtained by applying consensus clustering. The colour gradients from 0 to 1 represent the degree of consensus, with white corresponding to 0 and dark blue corresponding to 1. b The heatmap corresponding to the dendrogram in Figure a, which was generated using the pheatmap function with DNA methylation classifications, TNM stage, clinicopathological stage and histological type as the annotations