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Fig. 4 | BMC Medical Genomics

Fig. 4

From: Whole-exome sequencing reveals potential mechanisms of drug resistance to FGFR3-TACC3 targeted therapy and subsequent drug selection: towards a personalized medicine

Fig. 4

GO enrichment analysis of mutated genes pre- and post-pazopanib resistance. a GO enrichment analysis showed enriched biological processes were senescence and regulation of organelle organization pre-resistance. b Chromatin modification, regulation of transcription, and gland development were enriched post-resistance. Color gradient corresponded to significance of corrected p-values

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