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Fig. 5 | BMC Medical Genomics

Fig. 5

From: Identification of key genes and functions of circulating tumor cells in multiple cancers through bioinformatic analysis

Fig. 5

Different types of CTCs. CTCs were identified by the RNA in situ hybridization technique. Epithelial CTCs presented only Alexa Fluor 594 (Red color) labeled epithelial markers (EpCAM and CK8/18/19), mesenchymal CTCs exhibited only Alexa Fluor 488 (Green color) labeled mesenchymal markers (Vimentin and Twist), hybrid CTCs having both epithelial and mesenchymal markers were stained with both green and red immunofluorescent dyes

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