Table 1 Patient characteristics
Characteristic | All patients (N = 229) (%) | Frozen tissue cohort (N = 183) (%) | FFPE tissue cohort (N = 46) (%) |
|---|---|---|---|
Age - no. | |||
  < 50 | 20 (8.7) | 17 (9.3) | 3 (6.5) |
 50–70 | 124 (54.1) | 101 (55.2) | 23 (50.0) |
  > 70 | 85 (37.2) | 65 (35.3) | 20 (43.5) |
Gender - no. | |||
 Male | 145 (63.3) | 113 (61.7) | 32 (69.6) |
 Female | 84 (36.7) | 70 (38.3) | 14 (30.4) |
Clinical stage - no. | |||
 I | 53 (23.2) | 34 (18.6) | 19 (41.3) |
 II | 69 (30.1) | 59 (32.3) | 10 (21.7) |
 III | 82 (35.8) | 71 (38.8) | 11 (24.0) |
 IV | 25 (10.9) | 19 (10.4) | 6 (13.0) |
Location sampled - no. | |||
 Rectum | 177 (77.3) | 140 (76.5) | 37 (80.5) |
 Left Colon | 19 (8.3) | 17 (9.3) | 2 (4.3) |
 Right Colon | 21 (9.2) | 16 (8.7) | 5 (10.9) |
 Rectosigmoid Junction | 12 (5.2) | 10 (5.5) | 2 (4.3) |
Differentiation - no. | |||
 Well | 13 (5.7) | 12 (6.6) | 1 (2.2) |
 Moderate | 180 (78.6) | 145 (79.2) | 35 (76.0) |
 Poor | 28 (12.2) | 19 (10.4) | 9 (19.6) |
 Unknowna | 8 (3.5) | 7 (3.8) | 1 (2.2) |
Metastatic sites - no. | |||
 Liver only | 19 (8.3) | 15 (8.2) | 4 (8.7) |
 Lung only | 2 (0.9) | 1 (0.5) | 1 (2.2) |
 Liver and Lung | 1 (0.4) | 1 (0.5) | 0 (0.0) |
 Bladder | 1 (0.4) | 1 (0.5) | 0 (0.0) |
 Brain | 1 (0.4) | 1 (0.5) | 0 (0.0) |
Treatment after surgery - no. | |||
 With adjuvant therapy | 129 (56.3) | 109 (59.6) | 20 (43.5) |
 Without adjuvant therapy | 96 (42.0) | 74 (40.4) | 22 (47.8) |
 NA | 4 (1.7) | 0 (0.0) | 4 (8.7) |
Tumor size - cm | |||
 Median (range) | 4(1.5–13) | 4 (1.5–13) | 4(1.5–12) |
CEA - ng/mL | |||
 0.0–5.0 | 150 (65.5) | 125 (68.3) | 25 (54.3) |
  > 5.0 | 74 (32.3) | 53 (29.0) | 21 (45.6) |
 N/A | 5 (2.2) | 5 (2.7) | 0 (0.0) |