Table 4 Candidate drugs targeting key genes
From: Identification of intestinal flora-related key genes and therapeutic drugs in colorectal cancer
Gene | Drug | Score* | Refs. (PMID) |
|---|---|---|---|
CSF2 | Interferon alfa-2b | 2 | 10522033 |
CSF2 | Mechlorethamine | 2 | 10640980 |
CSF2 | Streptozotocin | 2 | 16342200 |
CSF2 | Procarbazine | 2 | 10640980 |
CSF2 | Temozolomide | 3 | 12610499, 16100942 |
CSF2 | Mycophenolic acid | 2 | 9822358 |
CSF2 | Nordihydroguaiaretic acid | 2 | 2453577 |
CSF2 | Idarubicin | 2 | 8915668 |
CSF2 | Cytarabine | 3 | 8819077, 8450676 |
CSF2 | Vinblastine | 2 | 10640980 |
CXCL8 | Paclitaxel | 2 | 9271387 |
CXCL8 | Bevacizumab | 1 | – |
CXCL8 | Aspirin | 2 | 12576442 |
CXCL8 | Leflunomide | 2 | 10902750 |
CXCL8 | Tretinoin | 2 | 8900181 |
CXCL8 | Cetuximab | 4 | 10614716, 15908664, 10037173 |
CXCL8 | Medroxyprogesterone acetate | 2 | 15914533 |
CXCL8 | Cyclophosphamide | 1 | – |
CXCL8 | Verapamil | 2 | 2686646 |
IL6R | Oprelvekin | 1 | – |
IL6R | Tocilizumab | 8 | 16899109 |
IL6R | Fluorouracil | 2 | 8888499 |
IL6R | Thalidomide | 2 | 12515619 |
CXCL10 | Oxaliplatin | 2 | 16101140 |