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Table 1 Clinical characteristics of the FHS Offspring participants included in this study (N = 198) at examination 8

From: Genome-wide transcriptome study using deep RNA sequencing for myocardial infarction and coronary artery calcification

N = 198

Early MI

(n = 55)

High CAC w/o MI

(n = 72)

Controls

(n = 71)

P-value

Age (years)

68.47 ± 7.80

67.73 ± 9.19

67.46 ± 5.78

0.76

Sex

42 M, 13F

30 M, 42F

36 M, 35F

0.00037

BMI (kg/m2)

29.07 ± 4.72

29.39 ± 5.60

28.99 ± 5.46

0.937

SBP (mmHg)

125.3 ± 17.62

132 ± 17.01

127.3 ± 15.06

0.064

DBP (mmHg)

69.02 ± 9.24

73.58 ± 10.49

74.49 ± 8.71

0.0041

TC (mg/dl)

154.7 ± 33.79

179.9 ± 34.22

183.2 ± 31.97

4.49E-06

TC_HDL

3.38 ± 1.12

3.62 ± 1.15

3.42 ± 0.97

0.41

Triglycerides (mg/dl)

126.4 ± 82.09

138.1 ± 87.1

114.4 ± 53.14

0.17

HDL (mg/dl)

48.69 + 14.53

53.06 + 13.94

57.58 (18.83)

0.009

Fasting glucose (mg/dl)

111.2 ± 30.76

112.5 ± 26.63

105 ± 14.85

0.16

Hypertension Rx (%)

54

47

37

1.02E-07

Diabetes Rx (%)

13

18

7

0.042

Lipid Rx (%)

51

46

32

1.78E-07

Cigarette use (current) (%)

9

5

2

0.02

Aspirin Rx (%)

44

43

31

0.0002

Diabetes mellitus (%)

11

15

9

0.04

  1. MI Myocardial infarction, CAC Coronary artery calcification, BMI Body mass index, SBP Systolic blood pressure, DBP Diastolic blood pressure, TC Total cholesterol, TC_HDL TC/HDL, HDL High-density lipoprotein cholesterol, Rx drug therapy