Skip to main content

Table 4 Risk SNV genotype counts by site and ancestry

From: Association between triglycerides, known risk SNVs and conserved rare variation in SLC25A40 in a multi-ancestry cohort

Site

APOC3

01

†APOA5

00/01/11/02

APOA1/C3/A4/A5

00/01/11

GCKR

00/01/11

INSR

00/01/11

CETP

00/01/11

CHOP

0

35/0/0/0

31/4/0

15/16/4

4/16/15

19/12/4

Cinc

3

286/1/0/0

183/89/15

156/94/37

37/94/156

151/91/45

Colu

8

611/7/0/0

416/180/22

276/263/79

79/263/276

300/238/80

Geis

10

1273/4/0/1

924/317/37

414/640/224

224/640/414

412/640/226

Harv

11

932/0/0/0

626/277/29

310/451/171

171/451/310

316/450/166

Mayo

3

2021/2/0/0

1435/537/51

695/982/346

346/982/695

642/989/392

Nwes

22

1951/9/2/0

1360/546/56

746/905/311

311/905/746

742/922/298

UWKP

5

1628/54/3/0

1132/487/66

607/764/314

314/764/607

637/809/239

Vand

0

146/0/0/0

110/34/2

53/64/29

29/64/53

36/77/33

Ancestry

AA

7

542/4/0/0

343/183/20

269/227/50

13/120/413

407/129/10

AS

0

595/55/5/0

376/245/34

306/274/75

149/322/184

315/286/54

EA

53

6930/5/0/1

5006/1752/178

2362/3396/1178

1271/3384/2281

2181/3440/1315

EA/AA

2

438/0/0/0

278/143/17

188/201/49

38/176/224

218/180/40

EA/AS

0

371/13/0/0

208/147/29

156/165/63

44/172/168

131/190/63

UN

0

7/0/0/0

6/1/0

3/4/0

0/5/2

3/3/1

Total

62

8883/77/5/1

6217/2471/278

3272/4179/1515

1515/4179/3272

3255/4228/1483

  1. APOC3 consists of 4 SNVs (rs76353203, rs147210663, rs138326449, rs140621530), APOA5 = rs2075291, APOA1/C3/A4/A5 gene cluster = rs964184, GCKR = rs1260326. INSR = rs1260326, CETP = rs7205804
  2. Chop Children’s hospital of Philadelphia, Cinc Cincinnati, Colu Columbia, Geis Geisinger, Harv Harvard, Mayo Mayo Clinic, news Northwestern, UWKP University of Washington and Kaiser Permanente Washington, Vand Vanderbilt, AA African American, AS Asian American, EA European American, UN unknown
  3. 00 = common genotype, 01 = heterozygote, 11 = alternate homozygote,
  4. †rs2075291 has three alleles. For this SNV, 02 = rare heterozygote (Allele 2 has frequency less than allele 1)