Table 3 GSEA analysis of main enrichment pathways of differential genes between low-risk group and high-risk group
From: Prognostic value of eight immune gene signatures in pancreatic cancer patients
Description | Set size | Enrichment score | NES | P value | P adjust | q values |
|---|---|---|---|---|---|---|
HALLMARK_ESTROGEN_RESPONSE_LATE | 196 | 0.480174 | 1.796374 | 0.001675 | 0.007284 | 0.003834 |
HALLMARK_MITOTIC_SPINDLE | 196 | 0.54578 | 2.04181 | 0.001675 | 0.007284 | 0.003834 |
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION | 194 | 0.595047 | 2.218997 | 0.001678 | 0.007284 | 0.003834 |
HALLMARK_GLYCOLYSIS | 197 | 0.54494 | 2.038302 | 0.001678 | 0.007284 | 0.003834 |
HALLMARK_MTORC1_SIGNALING | 194 | 0.473788 | 1.766808 | 0.001678 | 0.007284 | 0.003834 |
HALLMARK_P53_PATHWAY | 194 | 0.479256 | 1.787198 | 0.001678 | 0.007284 | 0.003834 |
HALLMARK_TNFA_SIGNALING_VIA_NFKB | 197 | 0.528313 | 1.97611 | 0.001678 | 0.007284 | 0.003834 |
HALLMARK_ESTROGEN_RESPONSE_EARLY | 192 | 0.488153 | 1.820779 | 0.001681 | 0.007284 | 0.003834 |
HALLMARK_HYPOXIA | 190 | 0.528445 | 1.971652 | 0.001681 | 0.007284 | 0.003834 |
HALLMARK_E2F_TARGETS | 189 | 0.637705 | 2.370316 | 0.001706 | 0.007284 | 0.003834 |
HALLMARK_G2M_CHECKPOINT | 188 | 0.680848 | 2.528334 | 0.001706 | 0.007284 | 0.003834 |
HALLMARK_INTERFERON_ALPHA_RESPONSE | 93 | 0.562764 | 1.918891 | 0.001748 | 0.007284 | 0.003834 |
HALLMARK_PANCREAS_BETA_CELLS | 40 | − 0.84889 | − 2.53883 | 0.002132 | 0.008201 | 0.004316 |
HALLMARK_ALLOGRAFT_REJECTION | 199 | − 0.3919 | − 1.50621 | 0.002469 | 0.008818 | 0.004641 |
HALLMARK_APICAL_JUNCTION | 194 | 0.425713 | 1.58753 | 0.003356 | 0.010411 | 0.00548 |
HALLMARK_MYC_TARGETS_V1 | 192 | 0.43265 | 1.613757 | 0.003361 | 0.010411 | 0.00548 |
HALLMARK_APOPTOSIS | 159 | 0.41949 | 1.510011 | 0.00354 | 0.010411 | 0.00548 |
HALLMARK_TGF_BETA_SIGNALING | 54 | 0.51843 | 1.605989 | 0.005495 | 0.015263 | 0.008033 |
HALLMARK_MYC_TARGETS_V2 | 58 | 0.521398 | 1.636302 | 0.007449 | 0.019602 | 0.010317 |
HALLMARK_INFLAMMATORY_RESPONSE | 197 | 0.37996 | 1.421208 | 0.008389 | 0.020849 | 0.010973 |
HALLMARK_UV_RESPONSE_DN | 137 | 0.397836 | 1.40847 | 0.008757 | 0.020849 | 0.010973 |
HALLMARK_BILE_ACID_METABOLISM | 112 | − 0.40053 | − 1.43725 | 0.011261 | 0.025594 | 0.01347 |
HALLMARK_ANDROGEN_RESPONSE | 97 | 0.429447 | 1.468431 | 0.015762 | 0.034265 | 0.018034 |