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Fig. 4 | BMC Medical Genomics

Fig. 4

From: DNA hypermethylation associated with upregulated gene expression in prostate cancer demonstrates the diversity of epigenetic regulation

Fig. 4

The UPUP-only group shows a weaker correspondence to the UPUP pattern compared to the UPDOWN-only group and the corresponding UPDOWN pattern, although a clear difference between two groups can be seen. Most of the UPDOWN-only DNA methylation probes are negatively correlated with the expression of corresponding genes, while a few are positively correlated positively. UPUP-only pattern includes some negatively correlated probes, but still the larger fraction shows positive correlation. Overall, the UPUP and UPDOWN patterns are clearly distinct

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