Fig. 3
From: Highly robust model of transcription regulator activity predicts breast cancer overall survival
Regulator based risk model of TCGA breast cancer patients. a The distribution of the significant regulator activities, patients’ survival status and gene expression signature were analyzed in the TCGA breast cancer patients. (i) Hormone receptor status and PAM50 molecular classification of breast cancer patients. (ii) Heatmap of the selected regulator activities profile. (iii) Patients overall survival status and time. Rows represent genes, and columns represent patients. The red dashed line represents the risk score median cutoff dividing patients into low-risk and high-risk groups. b Kaplan-Meier estimates of patient survival in high- and low-risk groups based on transcriptional regulator activities