Fig. 5
From: Highly robust model of transcription regulator activity predicts breast cancer overall survival
Association of the transcription regulator-based risk score with pathological and molecular features. The regulator risk score is shown for breast cancer stages in the TCGA cohort (a) and in a selected validation set GSE21653 (b). One-way ANOVA p values are provided. Cancer related pathways that were significantly altered in patients with high regulator risk scores included cell cycle (c) and PLK1 signaling pathways (d). Normalized enrichment score (NES) was used to evaluate the enrichment results