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Fig. 3 | BMC Medical Genomics

Fig. 3

From: Master and servant: LINC00152 – a STAT3-induced long noncoding RNA regulates STAT3 in a positive feedback in human multiple myeloma

Fig. 3

STAiR18 knockdown affects the vitality of INA-6 cells. Permanently IL-6-treated INA-6 cells were transfected with siRNAs targeting STAiR18 exons 1, 2 and 3, as well as a negative control siRNA. To compare the knockdown effects on cell vitality, a STAT3 knockdown was also conducted. Cell vitality was analyzed by determining Annexin-V- and PI-stained cell populations via flow cytometry (first panel), cellular ATP content using the CellTiter-Glo-kit (middle panel) and Caspase3-assay (third panel) after 24 h, 48 h and 72 h (n = 3). The indication of significances refers to the control

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BMC Medical Genomics

ISSN: 1755-8794

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