Table 2 The results of enrichment of autism-related diseases
From: Potential role of genomic imprinted genes and brain developmental related genes in autism
Category | Subcategory | Expected | Observed | P-value |
|---|---|---|---|---|
NIA human disease gene sets | Autistic Disorder | 3.84196 | 27 | 2.25E-20 |
NIA human disease gene sets | Mental Disorders | 33.3853 | 87 | 2.25E-20 |
NIA human disease gene sets | Schizophrenia | 19.8722 | 52 | 7.73E-11 |
NIA human disease gene sets | Mood Disorders | 2.38467 | 12 | 0.0000174 |
NIA human disease gene sets | Bipolar Disorder | 7.81641 | 23 | 0.0000261 |
NIA human disease gene sets | Substance-Related Disorders | 2.25219 | 11 | 0.0000615 |
NIA human disease gene sets | Attention Deficit Disorder with Hyperactivity | 4.10693 | 15 | 0.0000911 |
NIA human disease gene sets | Obsessive-Compulsive Disorder | 1.32482 | 8 | 0.00013362 |
NIA human disease gene sets | Nervous System Diseases | 55.3773 | 82 | 0.00032166 |
NIA human disease gene sets | Alcoholism | 6.22663 | 18 | 0.00036562 |
NIA human disease gene sets | Psychotic Disorders | 2.38467 | 10 | 0.00073627 |
NIA human disease gene sets | Disorders of Environmental Origin | 19.8722 | 37 | 0.00133675 |
NIA human disease gene sets | Bulimia | 1.32482 | 7 | 0.00152108 |
NIA human disease gene sets | Neurotic Disorders | 1.4573 | 7 | 0.00344979 |
NIA human disease gene sets | Antisocial Personality Disorder | 0.794889 | 5 | 0.00471419 |
NIA human disease gene sets | Heroin Dependence | 0.794889 | 5 | 0.00471419 |
NIA human disease gene sets | Anxiety Disorders | 1.58978 | 7 | 0.00600006 |
NIA human disease gene sets | Tourette Syndrome | 1.19233 | 6 | 0.00600006 |
NIA human disease gene sets | Tobacco Use Disorder | 3.04707 | 10 | 0.00606997 |
NIA human disease gene sets | Alzheimer Disease | 14.8379 | 28 | 0.00613592 |
NIA human disease gene sets | Depressive Disorder | 4.37189 | 12 | 0.0100685 |
NIA human disease gene sets | Parkinson Disease | 6.22663 | 15 | 0.0100914 |
NIA human disease gene sets | Eating Disorders | 0.927371 | 5 | 0.0102424 |
NIA human disease gene sets | Kidney Diseases | 2.78211 | 9 | 0.0110736 |
NIA human disease gene sets | Conduct Disorder | 0.662408 | 4 | 0.0194026 |
NIA human disease gene sets | Autistic Disorder | 3.84196 | 27 | 2.25E-20 |