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Table 1 Top 15 potential shared neoantigens based on TCGA-SKCM cohort. Recurrent mutations observed on TCGA-SKCM cohort. The amino acid (AA) residue changes caused by somatic mutations are highlighted in the (neo) epitopes sequences. The frequency represents the number of samples showing the corresponding mutation

From: neoANT-HILL: an integrated tool for identification of potential neoantigens

GeneAA changeNeoepitopeHLA haplotypeFrequency
RAC1P29SFSGEYITVHLA-A*02:0117/466
KLHDC7AE635KHTATVRAKKHLA-A*11:0112/466
INMTS212FYMVGKREFFCVHLA-A*02:019/466
CDH6S524LFLFSLAPEAAHLA-A*02:018/466
ZBED2E157KGTMALWASQRKHLA-A*11:018/466
CRNKL1S128FLQVPLPVPRFHLA-A*15:017/466
IL37S202LFLFQPVCKAHLA-A*02:017/466
SERPINB3E250KLSMIVLLPNKHLA-A*11:016/466
DNAJC5BE22KSTTGEALYKHLA-A*11:016/466
MYO7BE512KMSIISLLDKHLA-A*11:016/466
MORC1E878KIQNTYMVQYKHLA-A*11:016/466
SCN7AS445FIEMKKRSPIFHLA-A*15:016/466
PSG9E404KKISKSMTVKHLA-A*11:016/466
RAC1P29LFLGEYIPTVHLA-A*02:015/466
NUTF2Q20KSSFIQHYYKHLA-A*11:015/466