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Table 7 Results for interactions reported by Liu et al. [2]

From: Modified entropy-based procedure detects gene-gene-interactions in unconventional genetic models

SNP pairp SNP 1Gene 1p SNP 2Gene 2SubmodelLDTS pairp value
rs9275595:rs108071139.50E-63DQA2 (F5U)1.30E-05DQB2 (F3U)Multi0.00260.038434.08E-20
rs9275390:rs108071131.22E-56DQA2 (F5U)1.30E-05DQB2 (F3U)Multi0.00010.0391631.51E-20
rs9275390:rs20515491.22E-56DQA2 (F5U)4.96E-01DQB2 (Intron)Multi0.00740.0294377.13E-15
rs2858332:rs108071132.90E-06DQA2 (F5U)1.30E-05DQB2 (F3U)Epi0.00820.0435334.01E-23
rs7774434:rs108071135.09E-19DQA1 (F3U)1.30E-05DQB2 (F3U)Multi0.00350.0294437.07E-15
rs7774434:rs20515495.09E-19DQA1 (F3U)4.96E-01DQB2 (Intron)Multi0.00110.0423172.10E-22
rs9275390:rs69010841.22E-56DQA2 (F5U)1.39E-02DQB2 (F5U)Epi0.00880.0252161.89E-12
rs2858332:rs69010842.90E-06DQA2 (F5U)1.39E-02DQB2 (F5U)Multi0.00910.0435332.90E-21
  1. Submodel of interaction as detailed in Table 6, p SNP 1 and p SNP 2 as p-values from 1st order calculation,
  2. linkage disequilibrium (LD) between SNPs, TS pair as value of the test statistic from 2nd order calculation,
  3. p-value as result from 2nd order calculation