Table 3 Ultrasonic soft markers and SNP array
Groups | Number of fetuses | Number of abnormal CNVs | Pathogenic CNVs | VUS CNVs |
|---|---|---|---|---|
Single ultrasonic soft marker | 729 | 45 (6.2%) | 24 | 21 |
Short femur | 26 | 4 (15.4%) | 3 | 1 |
Mild tricuspid regurgitation | 16 | 2 (12.5%) | 1 | 1 |
Choroid plexus cyst | 54 | 4 (7.4%) | 1 | 3 |
Ventriculomegaly | 115 | 8 (7.0%) | 4 | 4 |
Absent nasal bone | 76 | 5 (6.6%) | 2 | 3 |
Thickened nuchal translucency | 302 | 18 (6.0%) | 11 | 7 |
Hyperechogenic bowel | 65 | 3 (4.6%) | 2 | 1 |
Echogenic intracardiac focus | 22 | 1 (4.5%) | 1 | 0 |
Two ultrasonic soft markers | 322 | 20 (6.2%) | 10 | 10 |
Three or more ultrasonic soft markers | 80 | 4 (5.0%) | 3 | 1 |