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Table 7 Haplotype analysis based on different genetic models

From: Association of PICK1 and BDNF variations with increased risk of methamphetamine dependence among Iranian population: a case–control study

Genetic models Haplotype P-value* OR Lower CI Higher CI
Multiplicative H3 0.0002 2.5 1.502 4.161
H2 0.009 0.678 0.505 0.91
H1 0.742 1.047 0.794 1.382
H4 0.745 0.84 0.292 2.416
Dominant H2 0.001 0.532 0.358 0.79
H3 0.007 2.123 1.217 3.704
H1 0.735 0.924 0.582 1.466
H4 0.762 0.838 0.266 2.643
Recessive H3 0.003 11.569 1.499 89.293
H1 0.436 1.175 0.782 1.766
H4 0.555 0.842 0.052 13.549
H2 0.651 0.867 0.466 1.611
Co-dominant H3 0.004 12.331 1.595 95.316
H2 0.006 0.627 0.326 1.206
H1 0.571 1.044 0.620 1.757
H4 0.840 0.838 0.052 13.492
  1. H1: TG; H2: TT; H3: AT; H4: AG; OR: Odds ratio; CI: Confidence interval; P-values were obtained from Chi-square tests. * Significant of P-value < 0.05; Significant P-value in bold