Fig. 3

Nuclear sizes in the GE1 and GE2 hepatocellular carcinoma (HCC) subtypes and non-tumourous (NT) tissue. Nuclear size (µM) was determined in NT tissue (n = 10), as well as in two distinctive subgroups of HCC that were defined by gene expression profiling, GE1 (n = 10) and GE2 (n = 11); 100 cells per sample were evaluated. The box plot diagram shows the distribution of nuclear sizes in each tissue group, where the horizontal line demonstrates median nuclear size, the boxes span the interquartile range, and the “antennas” represent the minimum and maximum observed values