Table 7 Top* TFBSs enriched in genes upregulated in GE1-HCC

V$AR_03

AR

14.1

2.39E−02

Tumour promoting [23]

Tumour promoting [24]

V$TFIIA_Q6

GTF2A1/GTF2A2

8.5

1.25E−02

General enhancement of gene transcription [25]

–

V$PR_01

PGR

7.1

5.47E−02

Tumour promoting [26]

Unclear [27]

V$HES1_Q2

HES1

7.1

1.79E−02

Tumour promoting [28]

Unknown

V$ZNF219_01

ZNF219

4.4

3.10E−14

Unknown

Unknown

V$AREB6_03

ZEB1

4

4.24E−03

Tumour promoting [29]

Tumour promoting [30, 31]

V$GCNF_01

NR6A1

3.2

2.99E−02

Tumour promoting [32]

Unknown

V$MAZR_01

PATZ1

2.7

2.16E−50

Tumour promoting [33]

Unknown

V$PAX4_04

PAX4

2.7

3.70E−02

Cell proliferation/survival promoting or tumour suppressing in different contexts [34]

Unknown

V$UF1H3BETA_Q6

UF1-HNF3B (not further identified)

2.6

3.09E−74

–

–

V$CACBINDINGPROTEIN_Q6

CAC-binding protein (not further identified)

2.5

1.87E−26

–

–

V$MTF1_Q4

MTF1

2.5

3.30E−04

Tumour promoting [35]

Unknown