Fig. 3
From: A novel recessive PDZD7 bi-allelic mutation in an Iranian family with non-syndromic hearing loss
![Fig. 3](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs12920-021-00884-4/MediaObjects/12920_2021_884_Fig3_HTML.png)
A schematic representation of the PDZD7 protein domains and the identified mutation p.I84T. a PDZD7 comprised of three conserved PDZ domains (yellow) and one HNLD domain (blue). All previously reported PDZD7mutations are shown and the new reported mutation is depicted in red. b Multiple alignment of PDZD7 protein sequence shows that the Ile residue at situation 84 is highly conserved across nine species