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Table 2 Distribution of biochemical variables and MTHFR C677T gene polymorphism among the hypertensive cases and controls

From: Methylenetetrahydrofolate reductase gene polymorphism, global DNA methylation and blood pressure: a population based study from North India

 

Controls

Cases

p-value

Folate [median (IQR)]

3.81 (2.7–6.7)

3.54 (2.6–5.5)

0.30

Vitamin B-12 [median (IQR)]

232 (187.2–326.5)

256 (197–384)

0.09

Homocysteine [median (IQR)]

19.30 (13.4–28.8)

19.40 (13.7–29.1)

0.69

MTHFR Genotype

   

 CC

178 (70.1%)

139 (67.1%)

0.79

 CT

65 (25.6%)

58 (28.0%)

 

 TT

11 (4.3%)

10 (4.8%)

 

 Hardy–Weinberg p-value

0.291

0.483

 

T allele frequency

0.17

0.18

0.738