Fig. 1

Differential circRNAs in PBMCs of SLE. A Scatterplot of circRNA expression variation and reproducibility between SLE and control samples. The values of X and Y axes in the scatterplot represent the normalized signal values of the samples (log2 scaled). The dots represent the expression level from low (blue, 2.32) to high (red, 14.6). The green lines illustrate the fold change. The circRNAs above the top green line and below the bottom green line exhibit > 2.0-fold change between SLE and controls. B Hierarchical clustering to distinguish differentially expressed circRNAs between SLE and control samples. Each column represents one sample, and each row represents one circRNA. The dendrogram shows the relationships among the sample expression levels