|
Genotype
|
N
|
% b
|
Phenotype
|
NTP+ Nc
|
NTP+ %d
|
OR (95%CI)
|
P value
|
|---|
|
Panel A
| | | | | | | |
|
*4/*4
|
18
|
58.0
|
Rap
|
7
|
38.9
|
0.19 (0.04–0.95)
|
0.036
|
|
*4/*5B
|
1
|
3.2
|
Int
|
1
|
100
|
–
|
–
|
|
*4/*6A
|
6
|
19.4
|
Int
|
4
|
66.7
|
1.9 (0.28–11.98)
|
0.517
|
|
*4/*7B
|
6
|
19.4
|
Int
|
5
|
83.3
|
5.4 (0.55–53.27)
|
0.118
|
|
*4/*5B,*6A,*7B a
|
13
|
42.0
|
Int
|
10
|
76.9
|
5.2 (1.06–26.0)
|
0.036
|
|
Genotype in genders
|
N
|
%b
|
Phenotype
|
NTP+ Nc
|
NTP+ %d
|
OR (95%CI)
|
P value
|
|---|
|
Panel B
| | | | | | | |
|
Male *4/*4
|
9
|
29.0
|
Rap
|
2
|
22.2
|
0.1 (0.01–0.65)
|
0.012
|
|
*4/*5B,*6A,*7Ba
|
10
|
32.3
|
Int
|
8
|
80.0
|
14.0 (1.54–127.2)
|
0.012
|
|
Female *4/*4
|
9
|
29.0
|
Rap
|
5
|
55.5
|
0.6 (0.04–0.97)
|
0.735
|
|
*4/*5B,*6A,*7Ba
|
3
|
9.7
|
Int
|
2
|
66.7
|
1.6 (0.10–24.7)
|
0.735
|
- Rap. Rapid, Int. intermediate
- aTotal of the variants
- bFrequency in the total sample
- cResponders to NTP treatment
- dFrequency of responders in each group
