Fig. 6
From: Genome-wide analysis of long noncoding RNA expression profile in nasal mucosa with allergic rhinitis
Differentially expressed lncRNAs in airway epithelial cells after allergen stimulation. a Diagram of the Leukocyte Transendothelial Migration pathway [33]. Three dysregulated mRNAs were associated with the Leukocyte Transendothelial Migration pathway in our microarray analysis. They are CXCL12 (also known as stromal cell-derived factor-1α, SDF-1α), THY1, and CLDN1 (shown as CAMs). Their positions in the Leukocyte Transendothelial Migration pathway have been highlighted in yellow. b Quantitative expressions of lnc-CXCL12-4, CXCL12, and CXCR4 were assessed by real-time RT–PCR from BEAS-2B cells treated with or without 100 μg/mL of OVA for 4 h. c Quantitative expressions of lnc-CXCL12-4 and CXCR4 were assessed by real-time RT–PCR from BEAS-2B cells treated with or without 100 μg/mL of OVA for 4 h. All qRT-PCRs were performed in triplicate, and the Δct values were calculated by using glyceraldehyde 3-phosphate dehydrogenase as the endogenous control. OVA: ovalbumin; *P < 0.01