| Risk ratio (95% confidence interval) | |||
---|---|---|---|---|
Whites | P value | African Americans | P value | |
(n = 8451) | (n = 2230) | |||
Genetic risk score | Â | Â | ||
GRS range/mean (SD) | 44–84/61.4 (5.3) |  | 32–63/ 46.5 (4.2) |  |
GRS per 1 allele increase | 1.02 (1.02–1.03) |  < 0.001 | 1.03 (1.02–1.04) |  < 0.001 |
GRS per 5 increment | 1.12 (1.10–1.14) |  < 0.001 | 1.17 (1.13–1.21) |  < 0.001 |
GRS lower tertile | 1.00 (ref) | Â | 1.00 (ref) | Â |
GRS second tertile | 1.12 (1.07–1.17) |  < 0.001 | 1.23 (1.14–1.33) |  < 0.001 |
GRS highest tertile | 1.28 (1.23–1.33) |  < 0.001 | 1.37 (1.27–1.48) |  < 0.001 |
Dietary pattern per 5 increment | Â | Â | Â | Â |
No. per dietary pattern | Â | Â | Â | Â |
Western | 1.21 (1.12–1.31) |  < 0.001* | 1.14 (0.97–1.33) | .102 |
Healthy | 1.03 (0.95–1.11) | .453 | 1.20 (0.99–1.47) | .070 |
High-fat dairy | 0.72 (0.66–0.79) |  < 0.001* | 0.81 (0.69–0.96) | .013* |