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Table 9 SNP–SNP interaction models analyzed by the MDR method

From: Association between STAT4 gene polymorphism and type 2 diabetes risk in Chinese Han population

Model Training Bal. Acc Testing Bal. Acc CVC OR (95% CI) p
rs3821236 0.532 0.515 9/10 1.35(1.03–1.77) 0.032*
rs3821236, rs897200 0.542 0.523 5/10 1.38(1.08–1.77) 0.011*
rs3821236, rs11889341, rs897200 0.555 0.499 5/10 1.52(1.19–1.96) 0.001*
rs3821236, rs11893432, rs11889341, rs897200 0.572 0.496 8/10 1.73(1.35–2.22)  < 0.0001*
rs3821236, rs11893432, rs11889341, rs7574865, rs897200 0.579 0.501 10/10 1.85(1.43–2.38)  < 0.0001*
  1. MDR multifactor dimensionality reduction, Bal. Acc. balanced accuracy, CVC cross–validation consistency, OR odds ratio,
  2. CI: confidence interval;
  3. p values were calculated using χ2 tests, *p < 0.05 indicates statistical significance