Evaluation of the effect of MTNR1B rs10830963 gene variant on the therapeutic efficacy of nateglinide in treating type 2 diabetes among Chinese Han patients

Table 1 Comparison of genotype and frequencies of MTNR1B rs10830963 polymorphism between T2DM patients and healthy subjects

Genotypes	Healthy subjects (n = 200)	T2DM patients (n = 200)	P value
MTNR1B rs10830963
CC	82(41.00%)	70(35.00%)
CG	98(49.00%)	90(45.00%)
GG	20(10.00%)	40(20.00%)	0.019^Δ*
Alleles
C	262(65.50%)	230(57.50%)
G	138(34.50%)	170(42.50%)	0.020^Δ*

The allelic frequencies are indicated in absolute values (percentage). ^ΔP values are determined by the Pearson chi-square test. *P < 0.05

ISSN: 1755-8794