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Table 2 Clinical Characteristics of six POLE Samples from the Mayo Clinic Ovarian Cancer Cohort

From: Frequent POLE-driven hypermutation in ovarian endometrioid cancer revealed by mutational signatures in RNA sequencing

Sample

POLE mutation

POLE TMB

Age, years

Histology

Stage

Grade

Vital status

P1

A456P

75.2

46

Endometrioid

III

2

Alive

P2

S297F

71.7

49

Endometrioid

I

3

Alive

P3

V411L

64.1

49

Endometrioid

III

3

Deceased

P4

P286R

28.6

46

Endometrioid

I

2

Alive

P5

P286R

21.6

49

Endometrioid

I

1

Alive

P6

V411L

5.8

51

Endometrioid

I

1

Alive

  1. POLE DNA polymerase epsilon, TMB tumor mutation burden
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BMC Medical Genomics

ISSN: 1755-8794

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