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Table 4 Pathways that are enriched among target genes of miRNA-3163

From: The expression of miR-513c and miR-3163 was downregulated in tumor tissues compared with normal adjacent tissue of patients with breast cancer

Nos Gene set Pathway name C E R FDR p valuea
1 hsa05170 Human immunodeficiency virus 1 infection 212 3.6155 3.3191 0.081094 2.5E−04
2 hsa04110 Cell cycle 124 2.1147 3.783 0.09676 1E−03
3 hsa04114 Oocyte meiosis 124 2.1147 3.783 0.09676 1E−03
4 hsa05202 Transcriptional misregulation in cancer 186 3.1721 3.1525 0.09676 1E−03
5 hsa04010 MAPK signaling pathway 295 5.0309 2.584 0.09676 1.5E−03
6 hsa05167 Kaposi sarcoma-associated herpesvirus infection 186 3.1721 2.8373 0.2378 4.4E−03
7 hsa04340 Hedgehog signaling pathway 47 0.80154 4.9904 0.3802 8.2E−03
8 hsa04310 Wnt signaling pathway 146 2.4899 2.8114 0.49589 1E−02
9 hsa05206 MicroRNAs in cancer 150 2.5581 2.7364 0.50585 1.4E−02
10 hsa04218 Cellular senescence 160 2.7286 2.5654 0.58131 2E−02
  1. C the total number of genes in the category, E number of expected genes in each category, R fold enrichment
  2. aThe Benjamini–Hochberg adjusted p value