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Table 5 Top ten enriched biological processes among target genes of miR-513c

From: The expression of miR-513c and miR-3163 was downregulated in tumor tissues compared with normal adjacent tissue of patients with breast cancer

No GO ID Biological process O FDR E R p valuea
1 GO: 0042148 Strand invasion 5 1 0.024004 83.32 2.2E−04
2 GO: 0006612 Protein targeting to membrane 187 1 0.89774 6.6834 2.7E−04
3 GO: 0045047 Protein targeting to ER 107 1 0.51368 7.7869 1.7E−03
4 GO: 0072599 Establishment of protein localization to endoplasmic reticulum 111 1 0.53289 7.5063 1.9E−03
5 GO: 0008340 Determination of adult lifespan 17 1 0.081613 24.506 2.9−E3
6 GO: 0006605 Protein targeting 412 1 1.9779 3.5391 3.6E−03
7 GO: 0090150 Establishment of protein localization to membrane 313 1 1.5026 3.993 3.9–03
8 GO: 0070972 Protein localization to endoplasmic reticulum 137 1 0.65771 6.0818 4.2E−03
9 GO: 0031297 Replication fork processing 95 1 0.15362 13.019 1E−02
10 GO: 0006614 SRP-dependent co-translational protein targeting to membrane 95 1 0.45607 6.5779 1E−02
  1. C the total number of genes in the category, E number of expected genes in the category, GO gene ontology, R fold enrichment, O number of observed target genes in each specific category
  2. aThe Benjamini–Hochberg adjusted p value