Skip to main content

Table 1 Cohort characteristics

From: Somatic mutations in benign breast disease tissues and association with breast cancer risk

  Cancer free at 16 years (N = 42) ER negative BC (N = 36) ER positive BC (N = 42) Total (N = 120) P value*
Age      0.416
   < 45 11 (26.2%) 11 (30.6%) 7 (16.7%) 29 (24.2%)  
 45–55 19 (45.2%) 14 (38.9%) 16 (38.1%) 49 (40.8%)  
   > 55 12 (28.6%) 11 (30.6%) 19 (45.2%) 42 (35.0%)  
Histologic impression      0.026
 Non-proliferative disease 25 (59.5%) 14 (38.9%) 19 (45.2%) 58 (48.3%)  
 Proliferative disease without Atypia 16 (38.1%) 19 (52.8%) 14 (33.3%) 49 (40.8%)  
 Atypical hyperplasia 1 (2.4%) 3 (8.3%) 9 (21.4%) 13 (10.8%)  
Atrophy      0.086
 N-miss 2 3 3 8  
 None 9 (22.5%) 13 (39.4%) 6 (15.4%) 28 (25.0%)  
 Partial 16 (40.0%) 13 (39.4%) 23 (59.0%) 52 (46.4%)  
 Complete 15 (37.5%) 7 (21.2%) 10 (25.6%) 32 (28.6%)  
Year of BBD      0.452
 Mean (SD) 1986 (8) 1987 (8) 1988 (9) 1987 (8)  
 Range 1969–1996 1970–1999 1972–2001 1969–2001  
  1. *Statistical comparisons for demographic variables across BBD group were conducted with Pearson’s chi-square test for categorical variables and ANOVA test for continuous variables