Table 1 Cohort characteristics
From: Somatic mutations in benign breast disease tissues and association with breast cancer risk
|  | Cancer free at 16 years (N = 42) | ER negative BC (N = 36) | ER positive BC (N = 42) | Total (N = 120) | P value* |
|---|---|---|---|---|---|
Age | Â | Â | Â | Â | 0.416 |
   < 45 | 11 (26.2%) | 11 (30.6%) | 7 (16.7%) | 29 (24.2%) |  |
 45–55 | 19 (45.2%) | 14 (38.9%) | 16 (38.1%) | 49 (40.8%) |  |
   > 55 | 12 (28.6%) | 11 (30.6%) | 19 (45.2%) | 42 (35.0%) |  |
Histologic impression | Â | Â | Â | Â | 0.026 |
 Non-proliferative disease | 25 (59.5%) | 14 (38.9%) | 19 (45.2%) | 58 (48.3%) |  |
 Proliferative disease without Atypia | 16 (38.1%) | 19 (52.8%) | 14 (33.3%) | 49 (40.8%) |  |
 Atypical hyperplasia | 1 (2.4%) | 3 (8.3%) | 9 (21.4%) | 13 (10.8%) |  |
Atrophy | Â | Â | Â | Â | 0.086 |
 N-miss | 2 | 3 | 3 | 8 |  |
 None | 9 (22.5%) | 13 (39.4%) | 6 (15.4%) | 28 (25.0%) |  |
 Partial | 16 (40.0%) | 13 (39.4%) | 23 (59.0%) | 52 (46.4%) |  |
 Complete | 15 (37.5%) | 7 (21.2%) | 10 (25.6%) | 32 (28.6%) |  |
Year of BBD | Â | Â | Â | Â | 0.452 |
 Mean (SD) | 1986 (8) | 1987 (8) | 1988 (9) | 1987 (8) |  |
 Range | 1969–1996 | 1970–1999 | 1972–2001 | 1969–2001 |  |