Table 1 Cohort characteristics
From: Somatic mutations in benign breast disease tissues and association with breast cancer risk
| Cancer free at 16 years (N = 42) | ER negative BC (N = 36) | ER positive BC (N = 42) | Total (N = 120) | P value* | |
|---|---|---|---|---|---|
| Age | 0.416 | ||||
| < 45 | 11 (26.2%) | 11 (30.6%) | 7 (16.7%) | 29 (24.2%) | |
| 45–55 | 19 (45.2%) | 14 (38.9%) | 16 (38.1%) | 49 (40.8%) | |
| > 55 | 12 (28.6%) | 11 (30.6%) | 19 (45.2%) | 42 (35.0%) | |
| Histologic impression | 0.026 | ||||
| Non-proliferative disease | 25 (59.5%) | 14 (38.9%) | 19 (45.2%) | 58 (48.3%) | |
| Proliferative disease without Atypia | 16 (38.1%) | 19 (52.8%) | 14 (33.3%) | 49 (40.8%) | |
| Atypical hyperplasia | 1 (2.4%) | 3 (8.3%) | 9 (21.4%) | 13 (10.8%) | |
| Atrophy | 0.086 | ||||
| N-miss | 2 | 3 | 3 | 8 | |
| None | 9 (22.5%) | 13 (39.4%) | 6 (15.4%) | 28 (25.0%) | |
| Partial | 16 (40.0%) | 13 (39.4%) | 23 (59.0%) | 52 (46.4%) | |
| Complete | 15 (37.5%) | 7 (21.2%) | 10 (25.6%) | 32 (28.6%) | |
| Year of BBD | 0.452 | ||||
| Mean (SD) | 1986 (8) | 1987 (8) | 1988 (9) | 1987 (8) | |
| Range | 1969–1996 | 1970–1999 | 1972–2001 | 1969–2001 |