From: Retinoblastoma genetics screening and clinical management
Phenotypic features | Mutation present n (%) | No mutation n (%) | Pearson Chi-square tests | |
---|---|---|---|---|
Chi sq | Significance (p value) | |||
Optic nerve invasion | ||||
Y | 11 | 8 | 1.83 | 0.575 |
N | 6 | 11 | Â | Â |
Recurrence | ||||
Y | 9 | 1 | 5.25 | 0.021 |
N | 20* | 20 | Â | Â |
Progression | ||||
Y | 16 | 1 | 13.79 | 0.000 |
N | 13 | 20 | Â | Â |
Need for topotecan | ||||
Y | 7 | 1 | 3.40 | 0.065 |
N | 22 | 20 | Â | Â |
Need for radiotherapy | ||||
Y | 3 | 2 | 0.091 | 0.923 |
N | 26 | 19 | Â | Â |