Table 5 GRADE Assessment
No of studies | Certainty assessment | Effect | Certainty | Importance | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Study design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other considerations | No of events | No of individuals | Rate (95% CI) | |||
Cannabis use in lifetime | |||||||||||
2 | Observational studies | Not serious | Not serious | Not serious | Not serious |  |  |  |  | – | IMPORTANT |
Diagnosis of cannabis use disorder | |||||||||||
2 | Observational studies | Not serious | Not serious | Serious a | Not serious |  |  |  |  | – | IMPORTANT |
Criterion count of cannabis use disorder | |||||||||||
2 | Observational studies | Not serious | Not serious | Serious a | Not serious |  | – |  |  | – | IMPORTANT |
Age of onset of cannabis use | |||||||||||
1 | Observational studies | Not serious | Not serious | Not serious | Not serious |  | – |  |  | – | IMPORTANT |