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Table 5 GRADE Assessment

From: Genetic basis of cannabis use: a systematic review

No of studies Certainty assessment Effect Certainty Importance
Study design Risk of bias Inconsistency Indirectness Imprecision Other considerations No of events No of individuals Rate (95% CI)
Cannabis use in lifetime
2 Observational studies Not serious Not serious Not serious Not serious      IMPORTANT
Diagnosis of cannabis use disorder
2 Observational studies Not serious Not serious Serious a Not serious      IMPORTANT
Criterion count of cannabis use disorder
2 Observational studies Not serious Not serious Serious a Not serious     IMPORTANT
Age of onset of cannabis use
1 Observational studies Not serious Not serious Not serious Not serious     IMPORTANT
  1. aDifferent diagnostic classification