Fig. 1
From: Profiling non-coding RNA levels with clinical classifiers in pediatric Crohn’s disease
Crohn’s disease versus controls DE ncRNAs. Using princomp, principal components of entire ncRNAs (n = 20,779) were calculated in ileal (n = 345) a and b rectal (n = 390) biopsies shows separate cluster for CD and non-IBD controls. c Volcano plot shows the DE analysis results from ileal samples and shows a total of 89 DE ncRNAs between CD and non-IBD controls d whereas in rectal biopsies, there were a total of 41 DE ncRNAs were identified e, f Hierarchical clustering in heatmap shows a clear separation of CD and non-IBD controls for 89 DE ncRNAs in ileal biopsies and 41 DE ncRNAs in rectal biopsies. g The log2FC of 130 DE ncRNAs obtained from both ileal and rectal biopsies are plotted. Each dot represents a CD specific DE ncRNA either in ileum or rectum. The ncRNA that are significant only in ileum, only in rectum, and both ileum and rectum are marked in dark red, light red and blue, respectively. h The CD specific DE ncRNAs with inverted effects in both ileum and rectum are plotted