Fig. 1
From: Variation p.R1045H in MYH7 correlated with hypertrophic cardiomyopathy in a Chinese pedigree
The information of the HCM pedigree. a The pedigree map of the HCM family in this study. II-02 is the proband. b Apical four-chamber view of patient II-02, showing a markedly thickened ventricular septum. RV: right ventricle, LV: left ventricle, IVS: ventricular septum, RA: right atrium, LA: left atrium. c The results of Sanger sequencing to verify the variant found by whole-exome sequencing. Partial electropherograms of the genomic region covering the MYH7 gene, with the representation showing the coding strand. Patients I-02, II-01, and II-02, which carry variant NM_000257.3: c.1370 T > G (p.Ile457Arg) in a heterozygous state. II-03 is an unaffected relative