Fig. 7
From: RNA sequencing of blood in coronary artery disease: involvement of regulatory T cell imbalance
Schematic representation of stress granule-regulated transcripts. Analysis of the transcripts associated with CAD (TRACs) indicated an apparent enrichment for transcripts previously known to be associated with stress granules, which are membrane-less aggregates of proteins and RNA formed when cells are exposed to a variety of stressors, listed on the left. Under stress, these TRACs, of which 10 are shown here (DDX, EDC3, etc.), translocate from active, translatable forms in the cytosolic machinery, to sequestered, inactive forms in the stress granule. Molecular images courtesy of www.somersault1824.com under a Creative Commons license