Association between genetic variants of the cholinergic system and postoperative delirium and cognitive dysfunction in elderly patients

Table 1 Patient characteristics for POD analysis (n = 745)

Characteristic	POD (n = 155) (20.8%)	No POD (n = 590) (79.2%)	P
Characteristic	n = 745
Age [years]	74 [70; 76]	71 [68; 75]	< 0.001^a
Sex
Female	73 (47.1%)	247 (41.9%)	0.24^b
Charlson Comorbidity Index	1.84 ± 1.5	1.33 ± 1.5	< 0.001^a
Duration of anesthesia [min]	305 [202; 470]	175 [107; 269]	< 0.001^a

Data is shown as median [IQR 25; IQR 75], or as mean ± SD. Categorical data is shown as frequencies (percentages). Differences between patient groups with and without POD were evaluated with Mann–Whitney U test (a) or Chi-Square Test (b), whereas a P ≤ 0.05 was considered as statistically significant
IQR, interquartile range; SD, standard deviation

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