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Table 2 The general results for the association between XRCC3 Thr241Met polymorphism with leukemia risk

From: Ethnicity-stratified analysis of the association between XRCC3 Thr241Met polymorphism and leukemia: an updated meta-analysis

Comparison Group N Test of association Mode Test of heterogeneity
OR 95% CI P χ2 P I2
T versus. C Overall 20 1.21 1.00–1.47 0.049 Random 96.21 0 80.3
Caucasian 12 1.20 1.02–1.40 0.026 Random 27.38 0.004 59.8
Asian 5 1.25 0.62–2.50 0.530 Random 49.34 0 91.9
African 3 0.91 0.52–1.58 0.727 Random 5.50 0.064 63.6
TT versus. CC Overall 20 1.39 1.04–1.86 0.027 Random 37.78 0.006 49.7
Caucasian 12 1.35 1.05–1.73 0.018 Fixed 15.69 0.153 29.9
Asian 5 2.05 0.74–2.66 0.169 Random 8.44 0.077 52.6
African 3 0.51 0.12–2.16 0.361 Random 5.65 0 64.6
TC versus. CC Overall 20 1.05 0.84–1.34 0.443 Random 32.99 0.005 55.8
Caucasian 12 1.07 0.86–1.32 0.123 Fixed 11.22 0.166 30.4
Asian 5 1.01 0.54–1.76 0.643 Random 9.62 0.078 54.8
African 3 1.25 0.77–1.98 0.255 Random 7.32 0.002 62.1
TT versus. TC + CC Overall 20 1.31 0.99–1.73 0.063 Random 39.41 0.004 51.8
Caucasian 12 1.31 1.04–1.64 0.023 Fixed 15.30 0.169 28.1
Asian 5 1.95 0.71–5.37 0.194 Random 8.42 0.078 52.5
African 3 0.45 0.12–1.69 0.239 Random 5.52 0.063 63.8
TT + TC versus. CC Overall 20 1.19 0.99–1.43 0.071 Random 49.23 0 61.4
Caucasian 12 1.18 0.97–1.44 0.104 Random 23.28 0.016 52.8
Asian 5 1.19 0.69–2.05 0.537 Random 22.31 0 82.1
African 3 1.03 0.57–1.87 0.928 Random 2.81 0.246 28.8
  1. Bold values emphasize P < 0.05
  2. OR odds ratio, 95% CI 95% confidence interval