Ethnicity-stratified analysis of the association between XRCC3 Thr241Met polymorphism and leukemia: an updated meta-analysis

Table 2 The general results for the association between XRCC3 Thr241Met polymorphism with leukemia risk

Comparison	Group	N	Test of association			Mode	Test of heterogeneity
Comparison	Group	N	OR	95% CI	P	Mode	χ²	P	I²
T versus. C	Overall	20	1.21	1.00–1.47	0.049	Random	96.21	0	80.3
	Caucasian	12	1.20	1.02–1.40	0.026	Random	27.38	0.004	59.8
	Asian	5	1.25	0.62–2.50	0.530	Random	49.34	0	91.9
	African	3	0.91	0.52–1.58	0.727	Random	5.50	0.064	63.6
TT versus. CC	Overall	20	1.39	1.04–1.86	0.027	Random	37.78	0.006	49.7
	Caucasian	12	1.35	1.05–1.73	0.018	Fixed	15.69	0.153	29.9
	Asian	5	2.05	0.74–2.66	0.169	Random	8.44	0.077	52.6
	African	3	0.51	0.12–2.16	0.361	Random	5.65	0	64.6
TC versus. CC	Overall	20	1.05	0.84–1.34	0.443	Random	32.99	0.005	55.8
	Caucasian	12	1.07	0.86–1.32	0.123	Fixed	11.22	0.166	30.4
	Asian	5	1.01	0.54–1.76	0.643	Random	9.62	0.078	54.8
	African	3	1.25	0.77–1.98	0.255	Random	7.32	0.002	62.1
TT versus. TC + CC	Overall	20	1.31	0.99–1.73	0.063	Random	39.41	0.004	51.8
	Caucasian	12	1.31	1.04–1.64	0.023	Fixed	15.30	0.169	28.1
	Asian	5	1.95	0.71–5.37	0.194	Random	8.42	0.078	52.5
	African	3	0.45	0.12–1.69	0.239	Random	5.52	0.063	63.8
TT + TC versus. CC	Overall	20	1.19	0.99–1.43	0.071	Random	49.23	0	61.4
	Caucasian	12	1.18	0.97–1.44	0.104	Random	23.28	0.016	52.8
	Asian	5	1.19	0.69–2.05	0.537	Random	22.31	0	82.1
	African	3	1.03	0.57–1.87	0.928	Random	2.81	0.246	28.8

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