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Table 3 Gene–environment interaction models identified by multiple linear regression analysis

From: An association study in the Taiwan Biobank elicits the GABAA receptor genes GABRB3, GABRA5, and GABRG3 as candidate loci for sleep duration in the Taiwanese population

Interaction model

P value

GABRB3 rs79333046, physical activity

2.08 × 10–3

GABRB3 rs79333046, coffee consumption

3.26 × 10–4

GABRB3 rs79333046, tea consumption

3.66 × 10–3

GABRB3 rs79333046, smoking

0.0345

GABRB3 rs79333046, alcohol consumption

NS

GABRA5 rs189790076, physical activity

NS

GABRA5 rs189790076, coffee consumption

3.42 × 10–3

GABRA5 rs189790076, tea consumption

NS

GABRA5 rs189790076, smoking

9.35 × 10–3

GABRA5 rs189790076, alcohol consumption

0.0134

GABRG3 rs147619342, physical activity

NS

GABRG3 rs147619342, coffee consumption

0.0112

GABRG3 rs147619342, tea consumption

4.59 × 10–3

GABRG3 rs147619342, smoking

0.0423

GABRG3 rs147619342, alcohol consumption

NS

  1. Analysis was obtained after adjustment for covariates, including age, gender, physical activity, coffee consumption, tea consumption, smoking, alcohol consumption, body mass index (BMI), and status of chronic disorders
  2. NS nonsignificant
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BMC Medical Genomics

ISSN: 1755-8794

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