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Table 2 Odds ratios of ANRIL tag SNPs for CAD by multivariable logistic regression analysis

From: Genetic and epigenetic associations of ANRIL with coronary artery disease and risk factors

SNP Model Cases (n) Controls (n) Adjusted OR (95% CI) P value
rs1004638 Genotype TT (Ref.) 27 68 1  
AT 206 208 2.13 (1.34–3.40) 0.001
AA 268 225 2.50 (1.58–3.95) < 0.001
AT + AA 474 433 2.32 (1.49–3.62) < 0.001
Ptrend      0.008
Allele T (Ref.) 260 344 1  
A 742 658 1.39 (1.15–1.69) < 0.001
rs1333048 Genotype AA (Ref.) 104 141 1  
AC 249 259 1.38 (1.01–1.88) 0.044
CC 147 97 2.02 (1.40–2.91) < 0.001
AC + CC 396 356 1.56 (1.16–2.09) 0.003
Ptrend      0.001
Allele A (Ref.) 457 541 1  
C 543 453 1.40 (1.17–1.67) < 0.001
rs1333050 Genotype CC (Ref.) 101 124 1  
CT 259 265 1.21 (0.88–1.66) 0.242
TT 142 109 1.58 (1.09–2.28) 0.015
CT + TT 401 374 1.32 (0.97–1.78) 0.074
Ptrend      0.027
Allele C (Ref.) 461 513 1  
T 541 483 1.24 (1.04–1.48) 0.018
  1. Ref.: reference variable; CAD: coronary artery disease; OR: odds ratio; CI: confidence interval. Trend test was examined by χ2 test (linear-by-linear association)