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Table 1 Descriptive table of demographic variables

From: Association of MTHFR C677T variant genotype with serum folate and Vit B12 in Iranian patients with colorectal cancer or adenomatous polyps

  Control* Case** p-value
Agea
  < 45 229 (45.8%) 86 (20.5%)  < 0.001
     ≥ 45 271 (54.2%) 333 (79.5%)  
Sex
 Female 261 (52.2%) 200 (47.7%) 0.2
 Male 239 (47.8%) 219 (52.3%)  
Addictionb
 No 387 (77.4%) 353 (84.2%) 0.0115
 Yes 113 (22.6%) 66 (15.8%)  
Tumor location
 Colon   206 (49.2%)  
 Rectosigmoid   213 (50.8%)  
  1. *Number of controls: 500; **number of cases: 419; Chi-squared test was used to determine the p-value; aa cut off of 45 years old was determined for age according to American Cancer Society Guidelines and US Preventive Services Task Force Recommendation Statement [19, 20]; btype of addiction = smoking (cigarette, hookah, opium)