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Table 3 Allelic distribution and Hardy Weinberg equilibrium

From: Association of MTHFR C677T variant genotype with serum folate and Vit B12 in Iranian patients with colorectal cancer or adenomatous polyps

Genotypes

Frequency (%)

Whole population

Controls

Cases

C/C

520 (56.58%)

305 (61%)

215 (51.31%)

C/T

273 (29.71%)

161 (32.2%)

112 (26.73%)

T/T

126 (13.71%)

34 (6.8%)

92 (21.96%)

Alleles

C

1313 (71.44%)

771 (77.1%)

542 (64.68%)

T

525 (28.56%)

229 (22.9%)

296 (35.32%)

HWE (p value)

8.07E−16

0.0566881

2.93E−17

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BMC Medical Genomics

ISSN: 1755-8794

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