Skip to main content

Table 6 The SNPs of CTNNA3 associated with susceptibility of type 2 diabetes in the subgroup tests (BMI)

From: CTNNA3 genetic polymorphism may be a new genetic signal of type 2 diabetes in the Chinese Han population: a case control study

SNP ID

Model

Genotype

BMI

OR (95% CI)

p

OR (95% CI)

p

 ≤ 24 (N = 326)

 > 24 (N = 426)

rs10822745

Allele

C/T

1.12 (0.81–1.54)

0.499

0.89 (0.68–1.17)

0.415

 

Homozygote

CC/TT

1.43 (0.69–2.95)

0.332

0.77 (0.44–1.37)

0.375

 

Heterozygote

CT

0.95 (0.58–1.56)

0.839

1.06 (0.68–1.67)

0.793

 

Dominant

CC-CT/TT

1.04 (0.64–1.67)

0.881

0.97 (0.63–1.50)

0.905

 

Recessive

CC/CT-TT

1.48 (0.77–2.85)

0.244

0.74 (0.45–1.22)

0.237

 

Log-additive

1.13 (0.81–1.59)

0.465

0.90 (0.68–1.19)

0.448

rs7920624

Allele

A/T

1.05 (0.76–1.44)

0.763

1.12 (0.85–1.47)

0.430

 

Homozygote

AA/TT

1.13 (0.56–2.26)

0.733

1.25 (0.72–2.17)

0.422

 

Heterozygote

AT

1.16 (0.66–2.04)

0.610

1.28 (0.81–2.02)

0.294

 

Dominant

AA-AT/TT

1.15 (0.67–1.99)

0.613

1.27 (0.83–1.95)

0.276

 

Recessive

AA/AT-TT

1.01 (0.58–1.77)

0.963

1.07 (0.67–1.72)

0.765

 

Log-additive

1.06 (0.75–1.51)

0.727

1.13 (0.86–1.49)

0.385

rs2441727

Allele

A/G

0.72 (0.48–1.08)

0.115

1.00 (0.70–1.41)

0.993

 

Homozygote

AA/GG

1.10 (0.19–6.24)

0.913

1.32 (0.32–5.51)

0.705

 

Heterozygote

AG/GG

0.64 (0.39–1.03)

0.068

0.96 (0.63–1.45)

0.829

 

Dominant

AA-AG/GG

0.66 (0.41–1.06)

0.082

0.97 (0.65–1.46)

0.896

 

Recessive

AA/AG-GG

1.30 (0.23–7.31)

0.765

1.34 (0.32–5.56)

0.689

 

Log-additive

1.16 (0.77–1.74)

0.484

1.00 (0.69–1.45)

0.991

rs7914287

Allele

T/C

1.57 (1.11–2.24)

0.072

1.45 (1.08–1.96)

0.014*

 

Homozygote

TT/CC

3.66 (1.43–5.36)

0.120

2.86 (1.32–6.24)

0.008*

 

Heterozygote

TC/CC

1.27 (0.79–2.06)

0.325

1.24 (0.82–1.88)

0.302

 

Dominant

TT-TC/CC

1.52 (0.96–2.42)

0.073

1.42 (0.96–2.11)

0.080

 

Recessive

TT/TC-CC

2.25 (1.31–4.07)

0.093

2.58 (1.22–4.47)

0.014*

 

Log-additive

1.60 (1.12–2.29)

0.110

1.48 (1.09–2.01)

0.013*

  1. OR, odds ratio; CI, confidence interval
  2. p < 0.05, bold text and '*' indicate statistical significance
  3. “–” indicates Log-additive model