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Table 6 The SNPs of CTNNA3 associated with susceptibility of type 2 diabetes in the subgroup tests (BMI)

From: CTNNA3 genetic polymorphism may be a new genetic signal of type 2 diabetes in the Chinese Han population: a case control study

SNP ID Model Genotype BMI
OR (95% CI) p OR (95% CI) p
 ≤ 24 (N = 326)  > 24 (N = 426)
rs10822745 Allele C/T 1.12 (0.81–1.54) 0.499 0.89 (0.68–1.17) 0.415
  Homozygote CC/TT 1.43 (0.69–2.95) 0.332 0.77 (0.44–1.37) 0.375
  Heterozygote CT 0.95 (0.58–1.56) 0.839 1.06 (0.68–1.67) 0.793
  Dominant CC-CT/TT 1.04 (0.64–1.67) 0.881 0.97 (0.63–1.50) 0.905
  Recessive CC/CT-TT 1.48 (0.77–2.85) 0.244 0.74 (0.45–1.22) 0.237
  Log-additive 1.13 (0.81–1.59) 0.465 0.90 (0.68–1.19) 0.448
rs7920624 Allele A/T 1.05 (0.76–1.44) 0.763 1.12 (0.85–1.47) 0.430
  Homozygote AA/TT 1.13 (0.56–2.26) 0.733 1.25 (0.72–2.17) 0.422
  Heterozygote AT 1.16 (0.66–2.04) 0.610 1.28 (0.81–2.02) 0.294
  Dominant AA-AT/TT 1.15 (0.67–1.99) 0.613 1.27 (0.83–1.95) 0.276
  Recessive AA/AT-TT 1.01 (0.58–1.77) 0.963 1.07 (0.67–1.72) 0.765
  Log-additive 1.06 (0.75–1.51) 0.727 1.13 (0.86–1.49) 0.385
rs2441727 Allele A/G 0.72 (0.48–1.08) 0.115 1.00 (0.70–1.41) 0.993
  Homozygote AA/GG 1.10 (0.19–6.24) 0.913 1.32 (0.32–5.51) 0.705
  Heterozygote AG/GG 0.64 (0.39–1.03) 0.068 0.96 (0.63–1.45) 0.829
  Dominant AA-AG/GG 0.66 (0.41–1.06) 0.082 0.97 (0.65–1.46) 0.896
  Recessive AA/AG-GG 1.30 (0.23–7.31) 0.765 1.34 (0.32–5.56) 0.689
  Log-additive 1.16 (0.77–1.74) 0.484 1.00 (0.69–1.45) 0.991
rs7914287 Allele T/C 1.57 (1.11–2.24) 0.072 1.45 (1.08–1.96) 0.014*
  Homozygote TT/CC 3.66 (1.43–5.36) 0.120 2.86 (1.32–6.24) 0.008*
  Heterozygote TC/CC 1.27 (0.79–2.06) 0.325 1.24 (0.82–1.88) 0.302
  Dominant TT-TC/CC 1.52 (0.96–2.42) 0.073 1.42 (0.96–2.11) 0.080
  Recessive TT/TC-CC 2.25 (1.31–4.07) 0.093 2.58 (1.22–4.47) 0.014*
  Log-additive 1.60 (1.12–2.29) 0.110 1.48 (1.09–2.01) 0.013*
  1. OR, odds ratio; CI, confidence interval
  2. p < 0.05, bold text and '*' indicate statistical significance
  3. “–” indicates Log-additive model