Association of single nucleotide polymorphisms with insulin secretion, insulin sensitivity, and diabetes in women with a history of gestational diabetes mellitus

Table 2 Association of SNPs with disposition index at 1–2 years postpartum in women previous GDM

SNP	Locus	Location	CHR	N	EA	B (SE)	p value
rs11708067	ADCY5	Intron	3	358	A	− 0.90 (0.38)	0.019
rs340874	PROX1	Intergenic	1	305	C	0.09 (0.15)	0.56
rs560887	G6PC2/ABCB11	Intron	2	303	C	0.027 (0.13)	0.83
rs10885122	ADRA2A	Intergenic	10	313	G	− 0.075 (0.37)	0.84
rs4607517	GCK	Intergenic	7	340	A	− 0.005 (0.17)	0.98
rs2191349	DGKB/TMEM195	Intergenic	7	368	T	− 0.07 (0.20)	0.72
rs7034200	GLIS3	Intron	9	342	A	− 0.04 (0.19)	0.82
rs7944584	MADD	Intron	11	303	A	− 0.24 (0.28)	0.40
rs174550	FADS1	Intron	11	304	T	− 0.001 (0.13)	0.99
rs10830963	MTNR1B	Intron	11	314	G	0.12 (0.18)	0.49
rs11605924	CRY2	Intron	11	365	A	− 0.60 (0.32)	0.064
rs7756992	CDKAL1	Intron	6	313	G	− 0.25 (0.20)	0.21

SNP = single nucleotide polymorphism, CHR = chromosome, EA = effect allele, B = beta/effect size, SE = standard error; N = number of women with successful genotyping

ISSN: 1755-8794