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Fig. 5 | BMC Medical Genomics

Fig. 5

From: Hub microRNAs and genes in the development of atrial fibrillation identified by weighted gene co-expression network analysis

Fig. 5

A The protein–protein interaction network of differentially expressed genes. The network contains the subset of proteins that form physical interactions with at least one other member. B Four molecular complex detection components identified by pathway and process enrichment analysis. C The construction of the miRNA-gene interaction network. The hub miRNAs are shown in dark pink, whereas the key genes are shown in light pink. The edge between two nodes represents the interaction between miRNAs and/or genes. D Nine hub genes identified by the ‘cytoHubba’ plugin via mixed character calculation. The significance of hub genes increases with increasing intensity of the dot color. miRNA, microRNA

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